Functional ultrastructure : Atlas of tissue biology and pathology
This atlas of functional ultrastructure provides a detailed insight into the complex structure and organization of cells and tissues, highlights specific cellular and tissue functions, and the dynamics of diverse intracellular processes. Highly informative electron micrographs are complemented by explanatory texts, selected references and schemes. The concept that subcellular organelles provide the structural foundation for fundamental processes of living organisms is emphasized. The first part covers the cellular organelles and changes due to experiments or occurring under pathological conditions. The second part illustrates by selected examples principles of functional tissue organization and typical changes resulting from experimental induction or pathological situations
eBook, English, ©2010
2nd, rev. and enl. ed View all formats and editions
SpringerWeinNewYork, Wien, ©2010
Atlas
1 online resource (xvii, 366 pages) : illustrations
9783211993903, 3211993908
663096046
Title Page; Copyright page; FOREWORD; PREFACE OF THE SECOND EDITION; PREFACE OF THE FIRST EDITION; ACKNOWLEDGEMENTS; WE ARE GRATEFUL TO THE FOLLOWING COLLEAGUES FOR PROVIDING MICROGRAPHS; Table of Contents; THE CELL; STRUCTURAL ORGANISATION OF A MAMMALIAN CELL; ARCHITECTURE OF THE CELL NUCLEUS; CYTOCHEMICAL DETECTION OF RIBONUCLEOPROTEINS; NUCLEAR LAMINA; DETECTION OF SITES OF DNA REPLICATION AND OF INTERPHASE CHROMOSOME DOMAINS; NUCLEOLUS; CHANGES OF THE NUCLEOLAR ARCHITECTURE; DETECTION OF SITES OF RNA SYNTHESIS; NUCLEAR PORE COMPLEXES. NUCLEAR PORE COMPLEXES: STRUCTURAL CHANGES AS MONITORED BY TIME-LAPSE ATOMIC FORCE MICROSCOPYMITOSIS AND CELL DIVISION; APOPTOSIS; VIRAL INCLUSIONS; SECRETORY PATHWAY OF PANCREATIC ACINAR CELLS; ENDOMEMBRANE SYSTEM OF DINOFLAGELLATES; RIBOSOMES, ROUGH ENDOPLASMIC RETICULUM; NUCLEAR ENVELOPE AND ROUGH ENDOPLASMIC RETICULUM; ANNULATE LAMELLAE; ROUGH ENDOPLASMIC RETICULUM: SITE OF PROTEIN TRANSLOCATION AND INITIATION OF PROTEIN N-GLYCOSYLATION; OLIGOSACCHARIDE TRIMMING, REGLUCOSYLATION, AND PROTEIN QUALITY CONTROL IN THE ROUGH ENDOPLASMIC RETICULUM. ROUGH ENDOPLASMIC RETICULUM: STORAGE SITE OF AGGREGATES OF MISFOLDED GLYCOPROTEINSRUSSELL BODIES AND AGGRESOMES REPRESENT DIFFERENT TYPES OF PROTEIN INCLUSION BODIES; SMOOTH ENDOPLASMIC RETICULUM; PROLIFERATION OF THE SMOOTH ENDOPLASMIC RETICULUM; PRE-GOLGI INTERMEDIATES; PRE-GOLGI INTERMEDIATES: OLIGOSACCHARIDE TRIMMING AND PROTEIN QUALITY CONTROL; GOLGI APPARATUS: A MAIN CROSSROADS ALONG SECRETORY PATHWAYS; PROTEIN SECRETION VISUALISED BY IMMUNOELECTRON MICROSCOPY; PROTEIN N-GLYCOSYLATION: OLIGOSACCHARIDE TRIMMING IN THE GOLGI APPARATUS AND PRE-GOLGI INTERMEDIATES. GOLGI APPARATUS: SITE OF MATURATION OF ASPARAGINE-LINKED OLIGOSACCHARIDESCELL TYPE-RELATED VARIATIONS IN THE TOPOGRAPHY OF GOLGI APPARATUS GLYCOSYLATION REACTIONS; CELL TYPE-RELATED DIFFERENCES IN OLIGOSACCHARIDE STRUCTURE; TOPOGRAPHY OF BIOSYNTHESIS OF SERINE/THREONINE-LINKED OLIGOSACCHARIDES; GOLGI APPARATUS AND TGN
STRUCTURAL CONSIDERATIONS; GOLGI APPARATUS AND TGN
SECRETION AND ENDOCYTOSIS; GOLGI APPARATUS, TGN AND TRANS GOLGI-ER; GOLGI APPARATUS, TGN AND TRANS GOLGI-ER: TILT SERIES; STRUCTURE OF THE TGN; BREFELDIN A-INDUCED GOLGI APPARATUS DISASSEMBLY. BREFELDIN A-TREATMENT: TUBULATION OF GOLGI APPARATUS AND ENDOSOMESBREFELDIN A-TREATMENT: EFFECT ON RETROGRADE TRANSPORT OF INTERNALISED WGA; BREFELDIN A-TREATMENT: TRANSITIONAL ER-ELEMENTS AND PRE-GOLGI INTERMEDIATES; HEAT SHOCK RESPONSE OF THE GOLGI APPARATUS; GOLGI APPARATUS CHANGES UPON ATP-DEPLETION AND ATP-REPLENISHMENT; SECRETORY GRANULES; SECRETORY GRANULE TYPES; GOBLET CELL
COMPOUND EXOCYTOSIS; RECEPTOR-MEDIATED ENDOCYTOSIS VIA CLATHRIN-COATED VESICLES AND VIRUS ENDOCYTOSIS; ENDOSOMES AND ENDOCYTIC PATHWAYS